Treatment volume definition for irradiation of primary lymphoma of the orbit: Utility of multimodality imaging
Journal of Surgery and Surgical Research
Objective: Irradiation may be utilized for management of orbital lymphomas with successful treatment results. However, adverse radiation effects may be considered as a concern particularly in the setting of higher delivered doses despite the excellent rates of tumor control in majority of irradiated patients. Multimodality imaging may serve as a contemporary approach for precise target defi nition in management of orbital lymphomas. Within this context, we assessed multimodality imaging based
... eatment volume defi nition for irradiation of primary lymphoma of the orbit in this original article. Materials and methods: Treatment volume defi nition by multimodality imaging with incorporation of MRI or by computed tomography (CT)-simulation images only was evaluated with comparative analysis in a series of patients receiving irradiation for orbital lymphoma. Results: Available treatment planning systems at our tertiary referral institution were used for precise radiation treatment planning. Prioritization was given for encompassing of the target volumes with optimal sparing of critical structures in radiation treatment planning. Synergy (Elekta, UK) LINAC was used in RT delivery. Treatment volume determination by CT-only imaging and by CT-MR fusion based imaging was assessed with comparative analysis. As a result, ground truth target volume was found to be identical with treatment volume defi nition with CT-MR fusion based imaging.