To describe the expecting ambulatory medical treatment in patients with Premature Rupture of Membranes (PRM), between 24 and 34 weeksof gestational age. Materials and methodology: An observationalstudy was made in patients with PRM and expecting ambulatorymedical treatment. Outcome: In this study, 14 patients between 20to 39 years of age with PRM between 25 to 33 weeks of gestationalage were included with a time period of 38 days of expecting treatment.The indications to terminate gestation

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... : presence ofspontaneous uterine activity (7 patients, 50%), chorio-amnionitis (1patient, 7.14%), intrahepatic cholestasis (1 patient, 7.14%), and fullterm delivery (4 patients, 28.5%). One of the patients presented aspontaneous closing of her membrane rupture and had a normaldelivery on her 39th week of pregnancy. The delivery was definedby obstetric indication so that 9 patients had normal delivery and5 patients had their deliveries by cesarean section, one of whichwas because of failed induction, and 4 of them due to a podalicpresentation. Conclusions: The expecting ambulatory medical treatmentis the one chosen for patients with PRM without clinical signsof maternal or fetal infection, and gestational ages between 24 to34 weeks. Although the expecting ambulatory medical treatmentis one of the correct choices, it is necessary that more controlledstudies be conducted to establish whether or not it is a therapeuticof choice for the expecting hospital medical treatment.