Características estruturais e ultraestruturais da junção miotendínea do músculo esternomastóideo de ratos Wistar recém-nascidos, adultos e idosos [thesis]

Adriano Polican Ciena
Ciena Ciena Ciena Ciena, meus ídolos, a quem devo tudo, sempre me apoiaram e souberam, pacientemente, compreender os caminhos da minha jornada. Com amor e profundo agradecimento: A minha amada Cristina de Sousa Bolina, os dias foram longos e as noites curtas entre objetivos, artigos, pesquisas e os nossos sonhos, agradeço imensamente pela companhia diária durante esses anos. Acompanhou e incentivou cada etapa da confecção da Tese e dos projetos paralelos, sempre paciente e pronta para ajudar.
more » ... onta para ajudar. Iremos continuar seguindo adiante, neste caminho, lado a lado e sempre de mãos dadas. Palavras-chave: Junção miotendínea. Músculo esternomastóideo. Envelhecimento. Microscopia eletrônica de varredura. Microscopia eletrônica de transmissão. ABSTRACT CIENA, A. P. Structural and ultrastructural features of myotendinous junction of the sternomastoid muscle of newborns, adults and aged Wistar rats. [Características estruturais e ultraestruturais da junção miotendínea do músculo esternomastóideo de ratos Wistar recém-nascidos, adultos e idosos]. 2013. 100 f. Tese (Doutorado em Ciências) -Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 2013. The myotendinous junction (MTJ) is the main area of power transmission and injuries of the musculoskeletal system, working on positioning and joint stabilization. The morphological study of the structures and ultrastructures of JMT muscle esternomastóideo (EM) demonstrated characteristics from birth, to reveal initial development, its complete training in adulthood and possible changes and compromises morphofunctional due to the physiological process of aging. The aim of this study is to describe the structural and ultrastructural features of JMT muscle EM Wistar rat newborns, adults and the elderly employing the methods of light microscopy, scanning electron microscopy and transmission electron microscopy. We used 45 Wistar rats into three groups (n = 15): Newborn Group: animals with 5 days of life; Adult Group: animals with 4 months of age; Group Aged: animals 24 months of age. The animals, after anesthesia, the muscles were dissected and the MTJ these were processed in accordance with the methods employed. The morphological characteristics of the JMT Group Newborn revealed his sketch during development, through the interaction of muscle cells and extracellular matrix elements, highlighting the slender folds sarcolemma and high cellular activity through numerous mitochondria oval crowded and tenoblastos. In Adult Group revealed classic features of JMT with highlight the folds of the sarcolemma forming long projections denominated evaginations and invaginations of the sarcoplasmic membrane. In Aged Group changes were observed in the MTJ with thickening at both levels of sarcoplasmic invaginations and in communications with the central lateral junctions, and thickening of collagen fibers and reduced cell in this area. We conclude that the JMT since the early stages of development to aging have intense training process, remodeling and changes due to the physiological process of aging.
doi:10.11606/t.10.2013.tde-18112013-103436 fatcat:2gui52axwjgxlozvmnilg775tu