Epidemiology of Malaria in Kanchipuram District Tamilnadu
Journal of Medical Science And clinical Research
Mosquito-borne diseases are the major concern in public health problems. Malaria is a protozoal disease caused by the parasites of the Genus Plasmodium -which are transmitted by the bite of female Anopheles mosquitoes. Prevalence of malaria worldwide is about 35%. Malaria infection diagnosed by Peripheral smear, Rapid Immunochromatography, and Molecular technique. Aim and Objective: To study the epidemiological distribution of Plasmodium infection in patients suspected for Pyrexia of Unknown
... rexia of Unknown Origin (PUO) attending a tertiary care hospital in Kanchipuram District, Tamilnadu. Methodology Study Design: This Study was carried out at Malarial parasites were identified in a peripheral blood smear by the conventional method (thick smear and thin smear), Rapid Immunochromatographic technique (a serological technique using whole blood) and Molecular technique. DNA extraction from whole blood done by Spine Column technique. Amplification and Gel Documentation done. Result: Total of 83 blood samples were collected from patients with a clinical diagnosis of PUO. Out of 83 samples, 5(6%) samples were positive for Plasmodium vivax species by conventional method, Rapid Immunochromatographic technique. The Molecular technique will help to diagnose the gene. Conclusion: In this study, Plasmodium vivax is identified more by conventional peripheral blood smear method as well as in Rapid Immunochromatographic method and Molecular Method.