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An interesting multicomponent complex has been prepared by incorporating a non -ionic homopolymer (e.g., Poly(Vinyl Pyrrolidone) PVP) on a typical copolymer (e .g., Methacrylic Acid/Acryl Amide MA/AAm). Stability constants and related thermodynamic parameters (e.g., Free energy change ∆F o , Enthalpy change ∆H o and Entropy change ∆S o ) have been determined. Interpretations have been sought in terms of secondary binding forces like hydrogen bonding, Van der Waals interactions and hydrophobicdoi:10.5897/ijps10.475 fatcat:tuysibhc2vhcrdzm34uksgohji