Seronegative disseminated Bartonella spp. infection in an immunocompromised patient

Claudia Weilg, Olguita Del Aguila, Fernando Mazulis, Wilmer Silva-Caso, Carlos Alva-Urcia, Rosario Cerpa-Polar, Erick Mattos-Villena, Juana Del Valle Mendoza
2016 Asian Pacific Journal of Tropical Medicine  
A B S T R A C T An 11 year old, hispanic girl with a history of B-cell acute lymphoblastic leukemia was admitted to the hospital for symptoms compatible with Bartonella henselae infection. The first molecularly diagnosed case of disseminated Bartonella henselae infection was reported in an immunocompromised patient in Lima, Peru. The analysis was confirmed by Polymerase Chain Reaction and automated sequencing of a liver biopsy sample, even though the serologic tests were negative. In
more » ... tive. In conclusion, Bartonella spp. infection should have a particular diagnostic consideration in immunocompromised patients with fever of unknown origin and further investigation regarding the patient's past exposures with cats should also be elicited.
doi:10.1016/j.apjtm.2016.11.001 pmid:27955752 fatcat:77vrbew4yncg3k4ax3woaepziu