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Periodontal tissue disease is one of the most widespread human diseases. The development of periodontal tissue diseases (generalized periodontitis) depends on many local and systemic risk factors. An important place is the emergence of diseases of periodontal tissues against the background of a violation of the normal functioning of antioxidant defense systems, which leads to the development of oxidative stress and dysfunction of cells and tissues of the oral cavity. The aim of the study was todoi:10.21802/gmj.2018.4.3 fatcat:zxqbtsluvrg37kgxi276slhfqq