Macropinocytosis Fuels Prostate Cancer

Cosimo Commisso, Jayanta Debnath
2018 Cancer Discovery  
Kim and colleagues identify necrotic debris as a macropinocytic cargo in PTEN-defi cient prostate cancer cells, which is catabolized to generate the nutrients and biomass necessary to support tumor cell growth and metabolism in nutrient-limiting conditions. Cancer Discov; 8(7); 800-2.
doi:10.1158/2159-8290.cd-18-0513 pmid:29967075 fatcat:3ma2hoalm5ftdn4jujqjcaqhri