The purpose of our study was to identify regional patterns of patients with acute pulmonary embolism, admitted to our hospital. Patients were divided into four groups of mortality risk: high, intermediate-high, intermediate-low and low risk. Treatment strategy and early mortality rate was followed. The highest early mortality rate was recorded in the high-risk PE group (20%), followed by the intermediate-high-risk group (15%) and the intermediate-low-risk group (7%), with no deaths in the

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... sk group. Some patients from the high and intermediate-high risk classes benefited from thrombolysis therapy. The number of PE patients that received VKA treatment was higher than that of the NOAC patients (59,33% vs 36%), but in the last years, we recorded a significant increase of NOAC use. Early mortality rate in PE remains high, especially in the high and intermediate-high risk classes. NOAC use in PE patients has become an option with a good efficacy/safety balance.