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Objective: To describe a patient with idiopathic zinc overload without an identifiable source and secondary copper deficiency causing myelopolyneuropathy and pancytopenia. Design: Case report. Patient and Results: A 46-year-old man presented with severe bone marrow suppression and subsequently developed progressive myelopathy with sensory ataxia. No identifiable cause of myelopathy was detected, and his neuroimaging findings were unremarkable. Plasma analysis demonstrated a low copper level anddoi:10.1001/archneur.60.9.1303 pmid:12975299 fatcat:fspevliu4beyxlieqkn72qr3ly