Towards an integrated framework for clinico-biological data management and analysis: The case of Chronic Lymphocytic Leukemia

Evangelia Minga, Athanasios Gkoufas, Anna Vardi, Evangelia Stalika, Anastasia Hadzidimitriou, Kostas Stamatopoulos, Nicos Maglaveras, Ioanna Chouvarda
2013 13th IEEE International Conference on BioInformatics and BioEngineering  
This paper addresses the challenges of gathering, analyzing and employing clinically meaningful biological information, for the advancement of translational medicine. In this respect we propose an approach for the integrated management and analysis of large quantities of clinicobiological data, including high-throughput sequencing data. The proposed concepts are applied in the case of Chronic Lymphocytic Leukemia, a paradigmatic age-related hematologic cancer, and the steps for data integration
more » ... and information analysis are illustrated via the CLL-BIND framework.
doi:10.1109/bibe.2013.6701690 dblp:conf/bibe/MingaGVSHSMC13 fatcat:ju2kixoqbneq5nly6sly3ih72a