(٨٩) (57. 15 12 .) (2)) 0.5) 30 (% 2 ,. . 75. (% 50.8). Escherichia coli.(% 27.5). (% 42.1) (% 73.3) (% 63.3) % 60 % 55.5 % 40 % 50 (% 25) (% 33.3). . Abstract The present study was conducted on 57 local breed cows suffering from various degrees of endometritis. The clinical examination included visual examination of vagina supported by uterine palpation per rectum; the laboratory examination included the bacterial isolation from the uterine swabs and histopathological examination of the

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... biopsies. Animals were randomly divided in to three groups of 15 cows each and 12 cows were considered as a control group received no treatment and observed for three consecutive estrous cycles. The first group was treated with a mixture of oxytetracycline (4 g) and tylosin (2 g), second group was treated with cephquenome sulfate 0.5 g, and the third group was treated with lugol's solution (30 ml) 2 %. These treatments were applied as a single intrauterine infusion and the clinical recovery was evaluated at the next estrous cycle by considering the absence of abnormal vagina discharge as an indicator of clinical recovery. Cows that showed clinical cure were inseminated artificially and the pregnancy diagnosis was preformed at least 75 days after insemination by rectal palpation. Retained placenta was the most important predisposing factor of endometritis 50.8 %, results of the bacterial examination demonstrated that E. coli was the most prevalence bacteria (27.4 %). Histopathological examination of uterine