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The main external environmental factors that influence the development of high-tech enterprises are identified in the article. As a result of the research, the interaction system of the external factors was developed, the correlation matrix was constructed, regression analysis was performed. This paper provides the necessity of practical application of the system of interaction of the external factors to increase the innovative activity of the high-tech enterprise.doi:10.1051/matecconf/201817001027 fatcat:4vuucezx4ndoresw4n45ecuupm