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BACKGROUND: Human sperm chemotaxis to pre-ovulatory follicular fluid is well established in vitro. However, it is not known whether the female's oocyte-cumulus complex secretes sperm chemoattractants subsequent to ovulation (for enabling sperm chemotaxis within the Fallopian tube) and, if so, which of these cell types-the oocyte or the cumulus oophorus-is the physiological origin of the secreted chemoattractant. METHODS: By employing a directionality-based chemotaxis assay, we examined whetherdoi:10.1093/humrep/deh657 pmid:15591080 fatcat:ccpjwlhlwbakte6uuy5cojmyrm