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Current Health Sciences Journal
VEGF receptors and their ligands are highly expressed in brain tumor cells but not in the adult normal brain cells. Angiogenesis process has been shown to play an important role in brain tumors cells development and survival. Malignant gliomas are the most common brain tumors with a low survival rate, despite the prompt treatment at diagnosis. Standard treatment consists of resection, radiation and chemotherapy with temozolomide, followed by 6 months of chemotherapy. Recurrence after standardfatcat:ndvacg3jsbhltn2o62a3rtaeci