A baffling case of severe systemic inflammation. Putting the pieces together: genes, environment and triggers

Geraint A Brown, Amma Kyei-Mensah, Helen J. Lachmann, Elena Nikiphorou
2017 Rheumatology  
Autoinflammatory syndromes are caused by an exaggerated innate immune system response and can pose important diagnostic challenges. They are often diagnosed by a combination of clinical findings and genetic testing. First presentation is often in childhood, although 10% of patients develop their first symptoms after the age of 30 1 .
doi:10.1093/rheumatology/kew505 pmid:28158814 fatcat:doivqubqzjgrriprn3suswiqfq