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Autoinflammatory syndromes are caused by an exaggerated innate immune system response and can pose important diagnostic challenges. They are often diagnosed by a combination of clinical findings and genetic testing. First presentation is often in childhood, although 10% of patients develop their first symptoms after the age of 30 1 .doi:10.1093/rheumatology/kew505 pmid:28158814 fatcat:doivqubqzjgrriprn3suswiqfq