A Study of Magnetic Drug Delivery System Using Bulk High Temperature Superconducting Magnet

S. Nishijima, S. Takeda, F. Mishima, Y. Tabata, M. Yamamoto, J. Joh, H. Iseki, Y. Muragaki, A. Sasaki, K. Jun, N. Saho
2008 IEEE transactions on applied superconductivity  
A magnetic drug delivery system (MDDS) has been studied to navigate and/or accumulate the magnetic seeded drug at a local diseased part in the human body. The bulk high temperature superconductors (HTS) are employed to control the drug because they would produce the required magnetic fields for MDDS. The trajectory of the ferromagnetic particles in the blood vessel was calculated and the possibility of the navigation of the drug is discussed. In the experiment the HTS (GdBaCuO) which produces
more » ... e magnetic field of 4.5 T at the surface, was located 25 mm apart from the Y-shaped blood vessel. The drug navigation probability to the desired direction was confirmed to be higher than 80%. A rat experiment was also performed successfully using a permanent magnet. The possible MDDS system will be discussed. Index Terms-Bulk high temperature superconductor, magnetic drug delivery system, magnetic seeded drug, nano-sized particle, navigation of drag.
doi:10.1109/tasc.2008.921967 fatcat:t2lzzfisprecnpznybb3bvvubm