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Asian Journal of Biomedical and Pharmaceutical Sciences
Ultra Fast liquid chromatography -mass spectrometry method (UFLC-MS), for detection and quantification of the anti-tuberculosis drug, ethambutol (EMB), in human plasma is described here. The method uses a single Quadrapole mass spectrometer equipped with positive electrospray ionization detector, linked with Shimadzu 20AD ultrafast LC system. Ethambutol was extracted from human plasma (100 µl) through a single step, simple and straight forward acetonitrile deproteinization method, achieving 98doi:10.15272/ajbps.v5i41.646 fatcat:rnokga3xizfdvpixlhhefkvnfi