Questionnaire (GHQ 30), Hospital Anxiety and Depression Questionnaire (HADQ) and the questionnaire related to sociodemographic variables were used. Results The demographic differences were not statistically significant. Social stigmatisation and the fear of transmitting to their partners were high among herpes. This difference is statistically significant at p < 0.001. The psychological distress among herpes group 66% (56/85) was significantly higher at p < 0.001 than the non herpes group 29%

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... 5/85).The level of anxiety and depression among herpes group was 35% (30/85) and 23.5% (20/85) respectively. For non herpes patients 15% (13/ 85) and 9% (8/85).The difference in the level of anxiety and depression among two groups was statistically significant at p < 0.05. Discussion/conclusion Patients with genital herpes had more psychological distress, anxiety and depression compared to non herpes patients.