A YO-cNG man, aged thirty, sought advice at Sir P. Dun's hospital on account of cramps in the stomach and lightness in the head, attended with shivering fits. He was ansemic ; the legs were swelled, but there was no albumen in the urine, either then or subsequently, Some months later be was admitted into hospital for severe abdominal pain, which had set in 13 days previously. He was very weak, and suffered from dry retching. His colour was sallow yellow; no leucocytosis. The abdomen was tensely

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... distended and very tender. It was dull at lower part and sides, and fluctuation could be detected. No enlargement of the cutaneous veins. A. systolic murmur was heard over the heart, at base and apex. The bowels were loose-four or five pasty motions in a day-and there was moderate pyrexia. He steadily became worse, and died in collapse, after a week's stay in hospital. Post-mortem-s-Live: normal in size, very hard and tough. Nodular cirrhosis, especially on under surface of left lobe. Gall bladder flaccid. About t1VO and a half quarts of thin serous fluid escaped from peritoneum. Spleen enlarged and firm. Portal vein adherent to structures in transverse fissure. It was much dilated, and its coats thick (about 3 mm.) and leathery-not calcified. Its interior was occupied by a firm yellowish granular thrombus adherent at one side to the vein but not completely obstructing its lumen. Branches of portal vein through the liver filled with soft thrombi, closely fitting, and yet capable of being withdrawn. Mesenteric veins occluded by soft red thrombi. The jejunum, for about one foot, was adherent to ascending colon by soft recent lymph. There was acute recent peritonitis over liver and over this portion of the bowel, which was intensely congested, and nearly black, resembling a strangulated intestine. No blood in its