Synthesis of new C-5-triazolyl-functionalized thymidine analogs and their ability to engage in aromatic stacking in DNA : DNA and DNA : RNA duplexes

Mick Hornum, Alevtina Djukina, Ann-Katrin Sassnau, Poul Nielsen
2016 Organic and biomolecular chemistry  
Stacking interactions of substituted triazoles in the major groove were studied, and with a polar uracil, increased duplex stabilities were found.
doi:10.1039/c6ob00609d pmid:27089052 fatcat:uwi4vj62zvebxg7aouxrkkg4ny