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Original Article MicroRNA-155 modulates the expression of pro-inflammatory cytokines in natural killer cells of rats exposed to chronic mild stress by regulation of ERK1/2 signaling pathway
Int J Clin Exp Pathol
Objectives: MicroRNAs (miRNAs) have been reported to be involved in depression. Besides, cell-mediated immunity (CMI) and inflammatory response system (IRS) are responsible for depression. The purpose of our study was to investigate the role of microRNA-155 (miR-155) in depression and the possible mechanism involving pro-inflammatory cytokines (PICs). Methods: Sprague-Dawley (SD) rats were randomly assigned to control and stress group. The rats in the stress group were subjected to chronic mildfatcat:2c7pdzxdzfaufhw6zmsjc2guom