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Impaired gastrocolonic response and peristaltic reflex in slow-transit constipation: role of 5-HT3 pathways
2002
American Journal of Physiology - Gastrointestinal and Liver Physiology
Impaired gastrocolonic response and peristaltic reflex in slow-transit constipation: role of 5-HT3 pathways. Am J Physiol Gastrointest Liver Physiol 283: G400-G407, 2002; 10.1152/ajpgi.00082.2001.-Colonic motility is modulated by the 5-hydroxytryptamine (5-HT) 3-dependent gastrocolonic response and 5-HT 3-independent peristaltic reflex. We compared descending colon tone responses to antral distension, duodenal lipid perfusion, and colonic distension after double-blind placebo or granisetron in
doi:10.1152/ajpgi.00082.2001
pmid:12121888
fatcat:u2344lveazcjdnrjwksg56xaxa