PROTEIN NETWORK COMPARATIVE GENOMICS

Trey Ideker
2006 Computational Systems Bioinformatics - Proceedings of the Conference CSB 2006  
With the appearance of large networks of proteinprotein and protein-DNA interactions as a new type of biological measurement, methods are needed for constructing cellular pathway models using interaction data as the central framework. The key idea is that, by comparing the molecular interaction network with other biological data sets, it will be possible to organize the network into modules representing the repertoire of distinct functional processes in the cell. Three distinct types of network
more » ... ct types of network comparisons will be discussed, including those to identify:
doi:10.1142/1860947573_0007 fatcat:isokt542brasvil4k6hgeuvtm4