Microwave-assisted synthesis and evaluation of antibacterial activity of novel 6-fluoroaryl-[1,2,4]triazolo[1,5-a]pyrimidines

2016 ARKIVOC  
A series of 6-fluoroaryl substituted [1,2,4]triazolo[1,5-a]pyrimidines have been synthesized by using the microwave-assisted Suzuki cross-coupling reaction from readily available 6-bromo-[1,2,4]triazolo[1,5-a]pyrimidine. The antimicrobial activity of new compounds has been evaluated in vitro against Mycobacterium tuberculosis H37Rv and gram-negative (Neisseria gonorrhoeae ATCC 49226) bacteria.
doi:10.3998/ark.5550190.p009.731 fatcat:3e4g7o5dsvdyvioyxwlbvgrk4q