Breast Carcinoma versus Benign Breast Lesions Diagnosed By Fine Needle Aspiration and Core Biopsies: Types, Age, Risk Factors, and Hormonal Receptors Status in Jordan
International Clinical Pathology Journal
Most studies regarding breast carcinoma risk factors compared it to the general population. In this study, we compare breast carcinoma risk factors to benign breast lesions. Material and methods: Breast core biopsies were performed from 610patients. Clinical history including the number of kids, lactation, oral contraceptive pills intake, abortions, smoking, age at menarche, and age at first pregnancy was taken. Results: In breast carcinoma cases, the average age was 50years vs 39years for
... n cases. Twenty-four percent of patients who had breast carcinoma were under 40years of age. Axillary lymph nodes showed metastatic carcinoma in 43% of breast carcinoma cases. Family history was positive for breast cancer in 20% in breast carcinoma cases vs 30% in benign breast lesions. No significant difference was found between the two groups regarding: no. of kids (4.2 vs 3.9), percentage of those having kids (77% vs 74%), age of menarche (13.2 vs 12.9y), and age at 1st pregnancy (22.2 vs 21.5y). Regarding lactation history, 32% of breast carcinoma patients did not lactate vs. 20% of patients with a benign breast lesion (P<0.05). Duration of lactation was similar in both groups. Other differences between the two groups (breast carcinoma cases vs benign breast lesions) were seen in contraceptive pills (33% vs 14%, P<0.009); smoking (21% vs 14%, P<0.05), and obesity. Cancer types were: Ductal (83%), lobular (10%), CIS (5%), and others (2%). Conclusion: Lactation is a protective factor. No differences were seen in: number of kids, menarche age, and age at 1st pregnancy. Factors associated with breast carcinoma were cigarette smoking, hormonal pills intake and obesity. Family history of breast carcinoma was associated more with benign lesions, probably due to that patients with positive family history were more worried about any breast lump than other people. Keywords : breast carcinoma risk factors in Jordan, types of breast carcinoma, core biopsy International Clinical Pathology Journal Research Article Open Access Breast carcinoma versus benign breast lesions diagnosed by fine needle aspiration and core biopsies: types, age, risk factors, and hormonal receptors status in Jordan 140 Copyright: ©2017 Farsakh et al. Citation: Farsakh SA, Farsakh HA. Breast carcinoma versus benign breast lesions diagnosed by fine needle aspiration and core biopsies: types, age, risk factors, and hormonal receptors status in Jordan.