A Case of Bone Marrow Recurrence from Gastric Carcinoma after a Nine-year Disease-free Interval

N. Noda, T. Sano, K. Shirao, H. Ono, H. Katai, M. Sasako, K. Maruyama
1996 Japanese Journal of Clinical Oncology  
W e present a case of very late and unusual recurrence of gastric cancer. Nine years following total gastrectomy for gastric carcinoma, a 57-year-old man presented with disseminated intravascular coagulation associated with bone marrow recurrence. The primary tumor was a signet ring cell carcinoma invading the subserosal layer with lymph node metastasis. The patient was treated with sequential administration of methotrexate and 5-fluorouracil and went into remission. After treatment, he
more » ... eatment, he survived 10 months. Autopsy revealed diffuse bone marrow infiltration and distant lymph node metastasis with signet ring carcinoma cells. (Jpn J Clin Oncol 26: 472-475, 1996)
doi:10.1093/oxfordjournals.jjco.a023267 pmid:9001355 fatcat:od3fjr3lpvftlgov24le6hdxnq