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Shaping the Output of Lumbar Flexor Motoneurons by Sacral Neuronal Networks
Journal of Neuroscience
The ability to improve motor function in spinal cord injury patients by reactivating spinal central pattern generators (CPGs) requires the elucidation of neurons and pathways involved in activation and modulation of spinal networks in accessible experimental models. Previously we reported on adrenoceptor-dependent sacral control of lumbar flexor motoneuron firing in newborn rats. The current work focuses on clarification of the circuitry and connectivity involved in this unique modulation anddoi:10.1523/jneurosci.2213-16.2016 pmid:28025254 fatcat:t74sfhlo4jdwtde6zxy64hlvna