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In vivo neuropathology of the hippocampal formation in AD: A radial mapping MR-based study
2006
NeuroImage
Early involvement of the hippocampal formation is the biological basis of the typical learning deficit in Alzheimer's disease (AD). However, the hippocampal formation is unevenly affected by AD pathology, deposits of plaques and tangles being particularly dense in the CA1 field and subiculum. The aim of the study was to locate in vivo the structural changes within the hippocampal formation in AD patients of mild to moderate severity. A group of 28 AD patients and 40 cognitively intact persons
doi:10.1016/j.neuroimage.2006.03.015
pmid:16631382
fatcat:4o65oigidffllkfvweh62nl6sy