Cloud Prediction of Protein Structure and Function with PredictProtein for Debian

László Kaján, Guy Yachdav, Esmeralda Vicedo, Martin Steinegger, Milot Mirdita, Christof Angermüller, Ariane Böhm, Simon Domke, Julia Ertl, Christian Mertes, Eva Reisinger, Cedric Staniewski (+1 others)
2013 BioMed Research International  
We report the release of PredictProtein for the Debian operating system and derivatives, such as Ubuntu, Bio-Linux, and Cloud BioLinux. The PredictProtein suite is available as a standard set of open source Debian packages. The release covers the most popular prediction methods from the Rost Lab, including methods for the prediction of secondary structure and solvent accessibility (profphd), nuclear localization signals (predictnls), and intrinsically disordered regions (norsnet). We also
more » ... t two case studies that successfully utilize PredictProtein packages for high performance computing in the cloud: the first analyzes protein disorder for whole organisms, and the second analyzes the effect of all possible single sequence variants in protein coding regions of the human genome.
doi:10.1155/2013/398968 pmid:23971032 pmcid:PMC3732596 fatcat:qx5dh4rp3vajhgsjcnhti2x7gy