Set-up and pilot of a population cohort for the study of the natural history of COPD and OSA: the PULSAIB study
Primary Care Respiratory Journal
Aims: We describe the set-up of a population-based study focussed on respiratory conditions, and describe a pilot study -the PULmons SAns Illes Balears (PULSAIB) study -aimed at investigating the natural history of COPD, obstructive sleep apnoea (OSA), and other common chronic diseases. Methods: A cross-sectional study was designed to survey two fieldwork areas, one rural and one urban, in the Balearic Islands, Spain. Tests conducted included a questionnaire, spirometry with post-bronchodilator
... post-bronchodilator (PBD) test, and portable respiratory polygraphy. Results: We assessed all processes and tools to be used, and piloted them in 175 participants from Bunyola (rural) and 130 participants from the Son Pizà area (urban). Within this first cross-sectional assessment of the Balearic population aged 30 to 80 years, we report the prevalence of airflow limitation defined as a PBD FEV1/FVC ratio <0.7 and the prevalence of OSA defined as an apnoea-hypopnoea index (AHI) >10/hour. Conclusion: A cohort study in the Balearic population to investigate the natural history of COPD and OSA is feasible.