Synthesis, Characterization and Antimicrobial Evaluation of Some Novel Bis-Schiff Bases

Khalid Patel, G Nazeruddin
2016 Journal of Chemical and Pharmaceutical Research   unpublished
We wish to report here with synthesis of bis-schiff bases via condensation of hydrazone of 2-hydroxy acetophenone with different substituted acetophenone in presence of SnCl 2 as a catalyst just by grinding to accomplish the bis-schiff base with moderate to good yields. All the synthesized Schiff bases were analyzed by spectral analysis IR, 1 H NMR and Mass spectrometry. All these bis-Schiff bases were screened for antimicrobial activity by using Agar Disc Diffusion method.