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Solution and solid state characterization of "sparteine surrogate" (+)-(1R,5S,11aS)-tetrahydrodeoxocytisine
2017
Bulgarian Chemical Communications
unpublished
The "sparteine surogate" (+)-(1R,5S,11аS)-tetrahydrodeoxocytisine is obtained by two known protocols, direct and two-step procedure, and is characterized in solution and solid state as free base, mono-, and bis-hydrochloride. Unambiguous assignment of the proton and carbon NMR spectra of tetrahydrodeoxocytisine is reported for the first time. X-ray and NMR data are compared and structural preferences in solid state and solution are discussed.
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