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An International, Multicenter, Placebo-Controlled Trial of Paroxetine in Adolescents with Major Depressive Disorder
Journal of child and adolescent psychopharmacology
Objective: The aim of this study was to examine the efficacy, safety, and tolerability of paroxetine in adolescents with unipolar major depression. Method: Two hundred eighty-six (286) adolescents with unipolar major depression were randomly assigned to receive either paroxetine or placebo for 12 weeks. Results: The proportion of Montgomery-Åsberg Depression Rating Scale (MADRS) responders (at least 50% reduction from baseline) for paroxetine and placebo were similar and not statisticallydoi:10.1089/cap.2006.16.59 pmid:16553529 fatcat:kkvpqwh55ba4vcq2owc3zv5jka