Studies on Antifungal Activity and Brine Shrimp Toxicity Argemone mexicana

Ainun Nahar, Anwar Habib, MA Awal, AKM Shahidur Rahman, MA Gafur Mondal, M Shah Alam
2017 KYAMC Journal  
<p>The present study determined the antifungal activity of the root of extracts Argemone mexicana against 7 fungi using dichloromethane and methanol as solvent. Among these pathogens, 3 were dermatophytes and the rest 4 were nondermatophytes. The dichloromethane extract of Argemone mexicana exhibited moderate to good activity at concentration of 200 μg/disc but at concentration of 50 μg/disc, the same extract showed no activity against the tested fungi. The methanol extract were also inactive
more » ... ainst the tested pathogens. In brine shrimp toxicity test, it was observed that LC50 value of the dichloromethane extract of Argemone mexicana was 22.35 μg/ml. From these findings it is indicative that dichloromethane extract of Argemone mexicana is biologically active and may have antifungal principles that could be useful in fungal diseases.</p><p>KYAMC Journal Vol. 4, No.-2, Jan 2014, Page 402-405</p>
doi:10.3329/kyamcj.v4i2.32279 fatcat:axeajtv4gnfgrcjq6ul3yqycn4