Therapeutics

1905 Journal of the American Medical Association (JAMA)  
serum a corresponding and compensating antidote to the poison which has been described by the Germans as syncytiolysin. If this compensatory or OA-ercoming serum is not sufficiently produced, then the poison is not counteracted. On the other hand, if the antidote is produced in too great an amount to be neutralized, it in turn acts as an irritating toxin. If it is a sound theory, as soon as the syncytial tissue ceases its activity, the patient should be relieved of the poison ; and, therefore,
more » ... ; and, therefore, emptying the uterus rather favors not the elimination of the poison, but the cessation of its production. Dr. O. Hopkinson, Jr., considered all methods of interfer¬ ing with pregnancy dangerous and only to be undertaken with an appreciation of the responsibility attached. The choice of the methods, he thinks, should be determined after a care¬ ful study of the case, as every case is a law unto itself. He prefers accouchement forcé in all cases in which the cervix has been previously dilated, that is, in multipara?. He uses the Goodell dilators to the full extent, and then the Harris or Edgar method and delivers by version or forceps or allows spontaneous termination, as the occasion demands. If there is no need or haste, he prefers the bougie, or packing with gauze. Both of these methods he considers uncertain, and if the patient shows signs of fever or rapid pulse, he terminates by accouchement forcé. Dr. Stricker Coles believes many cases are best treated
doi:10.1001/jama.1905.02500470065030 fatcat:suohqgvjq5canhb6lfbs5ge6xe