Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate

Naim Al-Said, Ayat Al-Sghair
2013 Molbank  
A simple route for synthesis of ethyl 2-(3-methyl-5-oxo-4,5-dihydro-3Hbenzo[e][1,4]diazepin-2-ylamino)benzoate is developed. The present work involves condensation of 2-(2-nitrobenzamido)propanoic acid with ethyl anthranillate followed by the H 2 /Pd/C reduction to give the amino ester which upon heating in DMF in the presence of FeCl 3 affords the title compound. The structure of the title compound was established on the basis of 1 H-NMR, 13 C-NMR and mass spectral data.
doi:10.3390/m811 fatcat:fktu622cfjgsrhfwoernoczzaq