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Trends in glycoscience and glycotechnology
Endotoxin is the major component of the outer leaflet of Gram-negative bacteria and expresses profound immunstimulatory and inflammatory capacity. The past years have provided new insights into the chemistry and biology of the endotoxin molecule. The knowledge about the submolecular structure of endotoxin, the synthesis of lipid A analogs and the development of endotoxin antagonists have provided an enormous body of information about the process of cellular activation by endotoxin. Furthermore,doi:10.4052/tigg.14.53 fatcat:fpxlodcjvrat5oso6zhhwv2hra