In this paper, a simple lossless image compression method based on a combination between bit-plane slicing and adaptive predictive coding is adopted for compressing natural and medical images. The idea basically utilized the spatial domain efficiently after discarding the lowest order bits namely, exploiting only the highest order bits in which the most significant bit corresponds to last layer7 used adaptive predictive coding, while the other layers used run length coding. The test results

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... s to high system performance in which higher compression ratio achieves for lossless system that characterized by guaranty fully reconstruction.