Opinions about mental illness have been found to be negative among college students and the general population. Studies have indicated that improving literacy levels would improve opinions and lead to individuals to seek help and family to provide the needed support. This study aimed to determine the effectiveness of psycho-education on the opinions about mental illness among public primary teacher trainees in Kenya. Convenience sampling was used to identify four public teacher colleges out of

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... he twenty. Self-administered demographic questionnaire and opinions about mental illness scale were presented to the participants to collect data in four evaluations for the experimental group and three for the control group. The ethical protocol was followed from getting authority to informed consent from the participants. Out of the 2925 questionnaires presented, 2775 were returned fully filled, a return rate of 94.34%. Summative scores improved among the experimental group in the second, and third assessments, but this reduced to almost the original measure in the fourth assessment. This study found that psycho-education of mental illness is effective in improving negative opinions about mental illness among these participants and this study recommended mental health studies is included in the teachers' curriculum.