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A tool for aligning very similar DNA sequences
1997
Bioinformatics
Results: We have produced a computer program, named sim3, that solves the following computational problem. Two DNA sequences are given, where the shorter sequence is very similar to some contiguous region of the longer sequence. Sim3 determines such a similar region of the longer sequence, and then computes an optimal set of single-nucleotide changes (i.e. insertions, deletions or substitutions) that will convert the shorter sequence to that region. Thus, the alignment scoring scheme is
doi:10.1093/bioinformatics/13.1.75
fatcat:3brmm33avjfcholmsfkmdyz4am