A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is
We have developed a method to visualize fluorescent protein-labeled ␤-cells in the intact pancreas through combined reflection and confocal imaging. This method provides a 3-D view of the ␤-cells in situ. Imaging of the pancreas from mouse insulin I promoter (MIP)-green (GFP) and red fluorescent protein (RFP) transgenic mice shows that islets, ␤-cell clusters, and single ␤-cells are not evenly distributed but are aligned along the large blood vessels. We also observe the solitary ␤-cells indoi:10.1152/ajpendo.00365.2005 pmid:16368785 fatcat:vbrbzhp5jfabpmkkexk62ncddu