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Flow Hydrodediazoniation of Aromatic Heterocycles
2019
Molecules
Continuous flow processing was applied for the rapid replacement of an aromatic amino group with a hydride. The approach was applied to a range of aromatic heterocycles, confirming the wide scope and substituent-tolerance of the processes. Flow equipment was utilized and the process optimised to overcome the problematically-unstable intermediates that have restricted yields in previous studies relying on batch procedures. Various common organic solvents were investigated as potential hydride
doi:10.3390/molecules24101996
fatcat:yllnqteo5rhlthcftty7bu2avq