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Chronic Skin Disease and Risk of Infection
The Open Infectious Diseases Journal
In this paper, we review the existing knowledge on the risk of infections in chronic skin disease. The normal skin is a major physiological barrier to most microorganisms. In patients with chronic skin diseases the epidermal barrier function is disrupted and the concentration of antimicrobial peptides may be reduced. Several case series and case-control studies of selected hospitalized patients confirm a high risk of colonization with S. aureus and cutaneous infections among patients withdoi:10.2174/1874279301206010060 fatcat:ks5gh6ticbawnpuscshfqbqczq