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Leprosy is a dynamic disease model in which distinct Mycobacterium leprae responsive T cell subsets play an important role in host defense and control clinical and immunological spectrum. Thl cells are associated with tuberculoid leprosy patients that have strong M leprac -specific CMI DTH responses. Th2 cells are expressed in lepromatous leprosy patients that are characterized by strong humoral immune responses and lack of T cell responses. Recently cytokines are thought to playdoi:10.5025/hansen.67.263 fatcat:hdmjr2vsy5eudcvpa3i2preh2m