Smoking and All-Cause Mortality in Older People

Carolin Gellert, Ben Schöttker, Hermann Brenner
2012 Archives of Internal Medicine  
Smoking is an established risk factor of premature death. However, most pertinent studies primarily relied on middle-aged adults. We performed a systematic review and meta-analysis of the empirical evidence on the association of smoking with all-cause mortality in people 60 years and older. Methods: A systematic literature search was conducted in multiple databases including MEDLINE, EMBASE, and ISI Web of Knowledge and complemented by crossreferencing to identify cohort studies published
more » ... ies published before July 2011. Core items of identified studies were independently extracted by 2 reviewers, and results were summarized by standard methods of meta-analysis. Results: We identified 17 studies from 7 countries. Current smoking was associated with increased all-cause mortality in all studies. Relative mortality (RM) compared with
doi:10.1001/archinternmed.2012.1397 pmid:22688992 fatcat:txtjuufgkbdyvagr6ofmasimrm