A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf
.
Trade-offs in Robustness to Perturbations of Bacterial Population Controllers
[article]
2020
bioRxiv
pre-print
Synthetic biology applications have the potential to have lasting impact; however, there is considerable difficulty in scaling up engineered genetic circuits. One of the current hurdles is resource sharing, where different circuit components become implicitly coupled through the host cell's pool of resources, which may destroy circuit function. One potential solution around this problem is to distribute genetic circuit components across multiple cell strains and control the cell population size
doi:10.1101/2020.06.04.134932
fatcat:7wl6ky37jbhojpvn54jpwqyyjy