A Comprehensive Review on Liquisolid Tablets

G Deepika, Madhu Gudipati, Rama Rao Nadendla
2021 International journal of pharmaceutical sciences review and research  
The Liquisolid process is a novel and effective approach to improving solubility. Bioavailability relies on drug solubility. With the evolution of modern pharmaceutical products, solubility is a big problem for the pharmaceutical industry. One of the most daunting aspects of drug production remains the enhancement of oral bioavailability of poorly water-soluble drugs. A newer methodology "powdered solution technology" or "Liquisolid technology", has been applied to prepare water-insoluble drugs
more » ... into rapid-release solid dosage forms. This method is efficient, economic, viable for industrial production, also useful in control drug delivery system. Hence due to above reasons Liquisolid technique is most efficient and novel approach for solubility enhancement. To prepare waterinsoluble drugs into rapid-release solid dosage forms, 'powdered solution technology' or 'Liquisolid technology' has been applied. This approach is reliable, cost-effective, viable for industrial production, and also useful in the drug delivery control system. Therefore, Liquisolid technique is the most effective and novel method for enhancing solubility due to the above factors.
doi:10.47583/ijpsrr.2021.v67i01.031 fatcat:bv6xj2xf2bgodh6fhxtx32is3u