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Galaxy is a popular framework for execution of complex analytical pipelines typically for large data sets, and is a commonly used for (but not limited to) genomic, genetic and related biological analysis. It provides a web front-end and integrates with high performance computing resources. Here we report the development of the blend4php library that wraps Galaxy's RESTful API into a PHP-based library. PHP-based web applications can use blend4php to automate execution, monitoring and managementdoi:10.1093/database/baw154 pmid:28077564 pmcid:PMC5225400 fatcat:a2xbof2gwncb5msce4fja6mcim