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Could Patient Self-reported Health Data Complement EHR for Phenotyping?
<span title="2014-11-14">2014</span>
<i title="American Medical Informatics Association">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/g6q27b56yzeupjryv6lby2r2pa" style="color: black;">AMIA Annual Symposium Proceedings</a>
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Electronic health records (EHRs) have been used as a valuable data source for phenotyping. However, this method suffers from inherent data quality issues like data missingness. As patient self-reported health data are increasingly available, it is useful to know how the two data sources compare with each other for phenotyping. This study addresses this research question. We used self-reported diabetes status for 2,249 patients treated at Columbia University Medical Center and the well-known
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<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25954446">pmid:25954446</a>
<a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4419899/">pmcid:PMC4419899</a>
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... GE EHR phenotyping algorithm for Type 2 diabetes mellitus (DM2) to conduct the experiment. The eMERGE algorithm achieved high specificity (.97) but low sensitivity (.32) among this patient cohort. About 87% of the patients with self-reported diabetes had at least one ICD-9 code, one medication, or one lab result supporting a DM2 diagnosis, implying the remaining 13% may have missing or incorrect self-reports. We discuss the tradeoffs in both data sources and in combining them for phenotyping.
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